The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects

Farah Fauzi, and Siti Balkis Budin, and Shahrul Azwan, and Leong, Kok Yuen (2007) The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects. Jurnal Sains Kesihatan Malaysia, 5 (2). pp. 39-52. ISSN 1675-8161

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Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic acid (AA) after a single bout of acute exercise. Twelve healthy, untrained young adult men were recruited for 5 weeks of aerobic training period. They were subjected to a rope-skipping exercise for 20 minutes at the intensity of 65 – 80% of heart rate reserve, thrice weekly. They also had to perform a single, acute bout of the same exercise protocol prior to and after training period. Venous blood samples were collected at resting condition (BL), immediately (0 h) and 24 hours (24 h) post acute exercise on both single bout sessions. Results showed that the pattern changes of oxidative stress response are quite similar on both acute sessions. The acute bouts of rope-skipping is associated with a significant increased (p= 0.001) in lipid peroxidation markers immediately after cessation of exercise, with a concomitant increase in antioxidant levels, albeit higher when compared to pre-training values (p = 0.001). These changes were followed by a significant decreased (p = 0.001) in all parameters, toward resting values, 24 hours thereafter. The training program seemed to induce a significant increase in MDA and 4-HNE but also enhanced the antioxidant defense system namely SOD and AA among the untrained subjects.

Item Type:Article
Keywords:Aerobic exercise; training; oxidative stress; free radicals; antioxidants
Journal:Jurnal Sains Kesihatan Malaysia
ID Code:1092
Deposited By: Mr Azhari Jamaludin
Deposited On:13 May 2011 07:22
Last Modified:14 Dec 2016 06:28

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