Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia

Rituparna Ghoshal, and Sharanjeet Kaur, and Norliza Mohamad Fadzil, and Somnath Ghosh, and NorFariza Ngah, and Roslin Azni Abd Aziz, (2018) Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia. Sains Malaysiana, 47 (10). pp. 2447-2454. ISSN 0126-6039


Official URL: http://www.ukm.my/jsm/malay_journals/jilid47bil10_...


The purpose of the present study was to assess quality of life (QOL) in n-AMD patients seen in a Malaysian public hospital and to further identify visual and demographic factors that may contribute to QOL scores of these patients. Patients with any form of n-AMD in at least one eye were recruited from hospital’s ophthalmology department. Bahasa Malaysia version of National Eye Institute Visual function questionnaire-25 (NEI-VFQ-25) was administered to all participants. Demographics, visual functions (VF) including best corrected distance visual acuity (BCDVA), contrast sensitivity (CS), near visual acuity (NVA) and reading speed (RS) were recorded. Eighty-six patients (Malay=26, Indian=23, Chinese=37) aged 52 to 85 years, diagnosed with n-AMD were chosen to participate. Their mean NEI-VFQ composite score (NEI-VFQ CS) was 66.91 ± 13.07. However, no significant difference in NEI-VFQ CS between gender, races and between the two sub groups of n-AMD were observed (p>0.05). NEI-VFQ CS showed a significant association with RS (correlation coefficient (ρ) =0.627), NVA (ρ = -.660), BCDVA (ρ = -.586), CS (ρ =.0.515). A linear model showed that a combination of BCDVA, NVA, CS is accounted for a significant 38 % variability of NEI-VFQ CS (R2 =0.382, p<0.001). In conclusion, the QOL of Malaysian n-AMD patients were found to be low. Thus, the study results indicated the need of developing necessary management strategies to address this QOL issues in n-AMD patients in Malaysia. Furthermore, the present study suggested incorporating appropriate VF such as near acuity, contrast sensitivity, reading speed in clinical settings while assessing n-AMD patients as these VF explain the patient’s perception about the impact of this disease.

Item Type:Article
Keywords:Neovascular AMD (n-AMD); Visual functions (VF); Vision targeted quality of life (VTQOL)
Journal:Sains Malaysiana
ID Code:12515
Deposited By: ms aida -
Deposited On:23 Jan 2019 07:51
Last Modified:28 Jan 2019 21:27

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