Ficus carica and bone health: a systematic review

Ruszymah Hj. Idrus, and Nur Qisya Afifah Veronica Sainik, and Ayu Suraya Ansari, and Mohamed S. Zulfarina, and Rabiatul Adawiyah Razali, and Abid Nordin, and Aminuddin Saim, and Isa Naina-Mohamed, (2018) Ficus carica and bone health: a systematic review. Sains Malaysiana, 47 (11). pp. 2741-2755. ISSN 0126-6039


Official URL:


Ficus carica, a native plant to the Middle East and Western Asia, is of high value in folk medicine. The therapeutic potential of Ficus carica has led to the extensive studies in recent years, focusing on evaluating and validating its pharmacological effect. The present systematic review summarizes the effectiveness of Ficus carica on promoting bone health focusing on osteoporosis and rheumatoid arthritis via mineral contents and RANKL pathway. The search was done with Medline via Ebscohost, Scopus and Google Scholar databases to obtain relevant articles published between 1946 and December 2016. The main inclusion criteria were research articles published in English that reported effect of Ficus carica on bone health. The literature search returned 716 potentially relevant articles, whereby 5 met the inclusion criteria. This systematic review concludes Ficus carica plays an important role in the promotion of bone health and can be a potential pharmaceutical product in the future.

Item Type:Article
Keywords:Bone; Ficus carica; Osteoporosis; RANKL pathway; Rheumatoid arthritis
Journal:Sains Malaysiana
ID Code:12656
Deposited By: ms aida -
Deposited On:11 Mar 2019 07:31
Last Modified:17 Mar 2019 11:24

Repository Staff Only: item control page