Local anaesthesia systemic toxicity (LAST) – A stroke mimicker

Faiezah K, and Tan, Toh Leong (2019) Local anaesthesia systemic toxicity (LAST) – A stroke mimicker. Medicine & Health, 14 (1). pp. 266-269. ISSN 2289-5728


Official URL: http://www.medicineandhealthukm.com/toc/14/1


Local anaesthesia systemic toxicity (LAST) is an uncommon and a potentially life-threatening event that develops after peripheral nerve block. The cause may be multifactorial and may include the choice of drug, technique of block and individual patient risk factors. We report a case of a 55-year-old female who developed slurring of speech and quadriplegia after receiving a mixture of lignocaine and hydrocortisone through an intra-articular injection to the right shoulder. Neurological examination revealed hypotonia and absence of power (0/5) in all limbs. These toxic events may have resulted from an accidental intra-arterialor dural cuff injection of local anaesthesia or absorption from surrounding tissues. This case report demonstrated that an intra-articular injection in the shoulder may cause LAST and may be under-recognized as it can mimic stroke.

Item Type:Article
Keywords:Intra-articular; Injection; Lidocaine; Local anaesthesia; Shoulder joint; Stroke
Journal:Medicine & Health
ID Code:15236
Deposited By: ms aida -
Deposited On:14 Sep 2020 07:16
Last Modified:21 Sep 2020 04:43

Repository Staff Only: item control page