Dini, Iwan and Soekamto, Nunuk Hariani and Firdaus, and Supratman, Unang and Jalifah Latip, (2021) Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne. Sains Malaysiana, 50 (9). pp. 2663-2674. ISSN 0126-6039
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Official URL: https://www.ukm.my/jsm/malay_journals/jilid50bil9_...
Abstract
Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported. Compounds (1) and (2) were isolated for the first time from this macroalga. Compund (1) were evaluated for their cytotoxicity activity against NCL-H460 lung cancer cells in vitro and showed moderate activity with IC50 value of 20.05 μg/mL.
| Item Type: | Article |
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| Keywords: | β-sitosterol; Caulerpin; Halimeda cylindracea; NCL-H460 lung cancer cells |
| Journal: | Sains Malaysiana |
| ID Code: | 18063 |
| Deposited By: | ms aida - |
| Deposited On: | 14 Feb 2022 07:32 |
| Last Modified: | 18 Feb 2022 00:48 |
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