Primary Thyroid Lymphoma: two different presentations of a rare disease

Azlin I, and Leong CF, and NH Hamidah, and Sharifah NA, and Rohaizak M, (2010) Primary Thyroid Lymphoma: two different presentations of a rare disease. Medicine & Health, 5 (2). pp. 114-119. ISSN 1823-2140


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Primary thyroid lymphoma is a rare disorder accounting for about 2% of all malignant lymphomas and less than 5% of thyroid malignancies. It is an aggressive disease with poor outcome. The majority of thyroid lymphomas are non-Hodgkin lymphomas of Bcell origin. Majority of cases occur in women in the sixth decade. We report two cases of primary thyroid lymphoma and highlight the clinical issues and challenges posed by this rare disease. Both cases presented with respiratory obstructive symptoms that required surgical intervention. The optimal management for a primary thyroid lymphoma be it chemotherapy, radiotherapy, surgery or monoclonal antibodies is still debatable. The role for surgery has evolved through the years but its importance in emergency situations should not be overlooked. Both our patients had to undergo surgery but only one patient received additional chemotherapy and radiotherapy. These two case reports illustrated the difficulties in managing this rare disorder.

Item Type:Article
Keywords:primary thyroid lymphoma; thyroid malignancies; malignant lymphoma
Journal:Medicine & Health
ID Code:2090
Deposited By: Mr Fazli Nafiah -
Deposited On:29 Jun 2011 03:25
Last Modified:14 Dec 2016 06:30

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