Sutarni, Yayan Dwi and Purwono, Bambang and Kunarti, Eko Sri and Mardjan, Muhammad Idham Darussalam (2023) Fe/ZSM-5-catalyzed-synthesis of 1,4-dihydropyridines under ultrasound irradiation and their antioxidant activities. Sains Malaysiana, 52 (4). pp. 1189-1202. ISSN 0126-6039
|
PDF
592kB |
Official URL: http://www.ukm.my/jsm/index.html
Abstract
A small library of 1,4-dihydropyridines have been synthesized from ethyl acetoacetate, ammonium acetate and various aldehydes via Hantzsch multicomponent reaction in the presence of Fe/ZSM-5 catalyst under ultrasound irradiation for 90 min. 1,4-Dihydropyridine derivatives were obtained in 64-86% yields and the heterogeneous Fe/ZSM-5 catalyst can be employed for four reaction cycles without losing the catalytic activity. All products were evaluated for their antioxidant activities using the DPPH method and compound 4g was found to be an effective antioxidant agent with DPPH activity of 83.5%.
| Item Type: | Article |
|---|---|
| Keywords: | Antioxidant assay Fe/ZSM-5 catalyst; Ultrasound-assisted-multicomponent reaction; 1,4-dihydropyridines |
| Journal: | Sains Malaysiana |
| ID Code: | 22068 |
| Deposited By: | Siti Zarenah Jasin |
| Deposited On: | 08 Aug 2023 08:31 |
| Last Modified: | 08 Aug 2023 08:31 |
Repository Staff Only: item control page
