A combined SEM and TEM studies of microsporum canis after in vitro treatment with atratoxin B1 from holothuria atra

Darah, I and Teo, M. L and Ibrahim , C. O (1996) A combined SEM and TEM studies of microsporum canis after in vitro treatment with atratoxin B1 from holothuria atra. Sains Malaysiana, 25 (1). pp. 87-97. ISSN 0126-6039

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Official URL: http://www.ukm.my/jsm/english_journals/vol25num1_1...

Abstract

Atratoxin B1 which was extracted from a local sea cucumber, Holothuria atra is a potential antifungal agent against dermatophytes. Exposure of Microsporum canis mycelia inoculated into Sabouraud glucose agar medium to the 10 mg/ml atratoxin B1 solution, resulted in complete suppression of the fungal growth. Prolonged exposure to the atratoxin B] (72 hours) resulted with necrosis in a substantial portion of the existing hyphae. The main anomalies noted were the abnormally shaped hyphae and the alterations in its morphology and cytology.

Item Type:Article
Keywords:Atratoxin B1;Microsporum canis
Journal:Sains Malaysiana
ID Code:3682
Deposited By: Mr Fazli Nafiah -
Deposited On:15 Mar 2012 06:49
Last Modified:29 Mar 2012 04:37

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