Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines

Ting, T.T.C. and Crouse, K.A. and Ahmad, H. (2015) Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines. Sains Malaysiana, 44 (4). pp. 619-628. ISSN 0126-6039

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Official URL: http://www.ukm.my/jsm/malay_journals/jilid44bil4_2...

Abstract

Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands.

Item Type:Article
Keywords:DNA binding; polypyridyl ligand; ruthenium(II) complex; transition metal complexes
Journal:Sains Malaysiana
ID Code:8641
Deposited By: ms aida -
Deposited On:27 May 2015 07:09
Last Modified:14 Dec 2016 06:47

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