Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis

Dayang Fredalina Basri, and Jacinta S., and Chong S.L, and Rohasmizah Ismail, (2004) Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis. Jurnal Sains Kesihatan Malaysia, 2 (2). pp. 97-102. ISSN 1675-8161

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Abstract

The aqueous and ethanol extracts of Stichopus chloronotus Brandt were investigated for their effectiveness against guinea pig dermatophytosis caused by Microsporum canis and Trichophyton mentagrophytes using the hair root invasion test. The ethanol extract at 10 mg/ml showed 82.8 % efficacy against T. mentagrophytes while the aqueous extract at similar concentration showed 84.8% efficacy against M. canis infection, as compared to econazole which showed 100% efficacy against both infections. No adverse effect on the skin was observed in the treated animals. In conclusion, aqueous and ethanol extracts of S. chloronotus showed high antimycotic activity against experimentally induced dermatophytosis in guinea pigs.

Item Type:Article
Journal:Jurnal Sains Kesihatan Malaysia
ID Code:971
Deposited By: Mr Azhari Jamaludin
Deposited On:28 Apr 2011 07:36
Last Modified:14 Dec 2016 06:28

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