Malaysian nasal polyps: eosinophil or neutrophil-predominant

Syuhada O, and Shalini P, and Lim, WK and Ammar A, and Suria Hayati Md Pauzi, and Aneeza Khairiyah Wan Hamizan, and Balwant Singh Gendeh, and Noraidah Masir, and Salina Husain, (2016) Malaysian nasal polyps: eosinophil or neutrophil-predominant. Medicine & Health, 11 (1). pp. 56-61. ISSN 1823-2140


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Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population.

Item Type:Article
Keywords:Eosinophil; Polyps; Histology
Journal:Medicine & Health
ID Code:9788
Deposited By: ms aida -
Deposited On:02 Jun 2016 03:15
Last Modified:14 Dec 2016 06:50

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